個人簡介

武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院副教授，圍繞生物醫(yī)用材料在疾病診斷、治療中的應(yīng)用，發(fā)展了系列新型生物功能材料。在Advanced Materials, Nature Communications, Biomaterials等國際頂級刊物共發(fā)表SCI論文47篇，主持和參與國家自然科學(xué)基金項目7項，企業(yè)橫向項目1項。研究方向為生物醫(yī)用高分子材料的設(shè)計及其應(yīng)用研究，包括藥物控釋，基因傳遞，分子影像等，近年來在腫瘤診療材料的研究領(lǐng)域做了大量系統(tǒng)性的研究工作，取得了不少具有創(chuàng)新性的成果。

教育經(jīng)歷

1999.09-2003.06    湖北大學(xué)化學(xué)系   大學(xué)本科

2003.09-2008.12    武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院   博士研究生

工作經(jīng)歷

2009.07-2021.11  武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院   講師

2016.10-2017.09  凱斯西儲大學(xué)生物工程學(xué)院       訪問學(xué)者

2021.11-至今       武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院   副教授

研究方向

藥物控釋，基因傳遞系統(tǒng)、腫瘤診療材料

代表成果

1.Dong, CY; Huang, QX; Cheng, H*; Zheng, DW; Hong, S; Yan, Y; Niu, MT; Xu, JG*; Zhang, XZ*, Neisseria meningitidis Opca Protein/MnO2 Hybrid Nanoparticles for Overcoming the Blood-Brain Barrier to Treat Glioblastoma, Adv. Mater., 2022,34,12:2109213

2.Wang, XG; Cheng, H*; Zhang, XZ, Flexible-on-rigid heteroepitaxial metal-organic frameworks induced by template lattice change, Nano Res., 2022,15,5:4693-4699

3.Yu, Y; Xie, BR; Liu, XH; Ye, JJ; Cheng, H*; Zhong, ZL*; Zhang, XZ*, A H2O2-responsive theranostic platform for chemiluminescence detection and synergistic therapy of tumors, J. Mat. Chem. B, 2021,12:5629

4.Zheng, DW; Pan, P; Chen, KW; Fan, JX; Li, CX; Cheng, H; Zhang, XZ*, An orally delivered microbial cocktail for the removal of nitrogenous metabolic waste in animal models of kidney failure, Nat. Biomed. Eng, 2020,4,9:853

5.Wan, SS; Liu, MD; Cheng, Q; Cheng, H*; Zhang, XZ*, A Mitochondria-Driven Metabolic Sensing Nanosystem for Oxygen Availability and Energy Blockade of Cancer, Adv. Therap., 2020,3,6:2000019

6.Chen, ZX; Liu, MD; Guo, DK; Zou, MZ; Wang, SB; Cheng, H*; Zhong, ZL; Zhang, XZ*, A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis, Nanoscale, 2020,12,5:2966-2972

7.Peng, MY; Wang, XQ; Zhang, Y; Li, CX; Zhang, MK; Cheng, H*; Zhang, XZ*, Mitochondria-Targeting Thermosensitive Initiator with Enhanced Anticancer Efficiency, ACS Appl. Bio Mater., 2019,2,10:4656-4666

8.Zhang, AN; Wu, W; Zhang, C; Wang, QY; Zhuang, ZN; Cheng, H*; Zhang, XZ*, A versatile bacterial membrane-binding chimeric peptide with enhanced photodynamic antimicrobial activity, J. Mat. Chem. B, 2019,7,7:1087-1095

9.Li, RQ; Zhang, C; Xie, BR; Yu, WY; Qiu, WX; Cheng, H*; Zhang, XZ*, A two-photon excited O-2-evolving nanocomposite for efficient photodynamic therapy against hypoxic tumor, Biomaterials, 2019,194:84-93

10.Wan, SS; Zeng, JY; Cheng, H*; Zhang, XZ*, ROS-induced NO generation for gas therapy and sensitizing photodynamic therapy of tumor, Biomaterials, 2018,185:51-62