個(gè)人簡(jiǎn)介

武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院教授，博士生導(dǎo)師。湖北省儀器儀表協(xié)會(huì)常務(wù)理事，湖北省化學(xué)化工學(xué)會(huì)理事，中國(guó)抗癌協(xié)會(huì)納米腫瘤學(xué)專業(yè)委員會(huì)委員會(huì)委員，中國(guó)生物材料學(xué)會(huì)納米生物材料分會(huì)委員，中國(guó)生物醫(yī)學(xué)工程學(xué)會(huì)納米醫(yī)學(xué)與工程分會(huì)委員，醫(yī)學(xué)檢驗(yàn)工程分會(huì)委員。2006年獲教育部高等學(xué)校自然科學(xué)一等獎(jiǎng)(第二完成人)，2017年獲湖北省自然科學(xué)一等獎(jiǎng)（第三完成人），2010年入選教育部“新世紀(jì)優(yōu)秀人才支持計(jì)劃”，2013年獲湖北省青年科技獎(jiǎng)，2014年入選武漢市“3551”光谷人才計(jì)劃。主要從事納米生物醫(yī)學(xué)傳感、微流控芯片及生物電化學(xué)等方面的研究工作。主要研究興趣包括磁控微流控芯片用于疾病標(biāo)志物檢測(cè)及腫瘤細(xì)胞分選，基于微流控芯片（器官芯片）的病毒與宿主細(xì)胞相互作用研究，液滴微流控用于納米材料合成及單顆粒數(shù)字化分析，超靈敏電化學(xué)傳感用于病原體檢測(cè)。國(guó)家基金委“新型生物醫(yī)學(xué)探針技術(shù)基礎(chǔ)及應(yīng)用”創(chuàng)新研究群體及教育部“化學(xué)生物學(xué)應(yīng)用基礎(chǔ)研究”創(chuàng)新團(tuán)隊(duì)骨干成員。主持6項(xiàng)國(guó)家自然科學(xué)基金、1項(xiàng)國(guó)家863重大項(xiàng)目子課題以及1項(xiàng)863專題課題，參加多項(xiàng)973項(xiàng)目及國(guó)家重大科學(xué)研究計(jì)劃項(xiàng)目。已在Angew Chem. Int. Ed.，Anal. Chem.，Biomaterials，Lab Chip，Biosens. Bioelectron.等國(guó)際雜志上發(fā)表SCI學(xué)術(shù)論文200余篇。

教育經(jīng)歷

1993.09-1997.06    吉林大學(xué)化學(xué)系    大學(xué)本科

1997.09-2002.11    武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院    碩博連讀

工作經(jīng)歷

2001.07-2005.11    武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院    講師

2003.10-2004.10    法國(guó)巴黎高等師范學(xué)校    博士后

2005.12-2008.11    武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院    副教授

2008.12-至今         武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院    教授

研究方向

磁控微流控芯片用于疾病標(biāo)志物檢測(cè)、高靈敏電化學(xué)傳感

代表成果

1. Bai Yi-Yan; Feng Zhi-Tao; Yang Yu-Jun; Yang Xiao-Yan; Zhang Zhi-Ling*, Current Lifetime of Single-Nanoparticle Collision for Sizing Nanoparticles, Analytical Chemistry, 2022, 94(2):1302-1307.

2. Yang Xiao-Yan; Bai Yi-Yan; Huangfu Yue-Yue; Guo Wen-Jing; Yang Yan-Ju; Pang Dai-Wen; Zhang Zhi-Ling*, Ultrasensitive Electrochemiluminescence Biosensor Based on Closed Bipolar Electrode for Alkaline Phosphatase Detection in Single Liver Cancer Cell, Analytical Chemistry, 2021, 93(3):1757-1763.

3. Tian Yishen; Xu Chun-Miao; Feng Jiao; Huangfu Yueyue; Wang Kai; Zhang Zhi-Ling*, Personalized Gel-Droplet Monocyte Vaccines for Cancer Immunotherapy, Lab on a Chip, 2021, 21(22):4414-4426.

4. Bai Yi-Yan; Wu Zhen; Xu Chun-Miao; Zhang Li; Feng Jiao; Pang Dai-Wen; Zhang Zhi-Ling*, One-to-Many Single Entity Electrochemistry Biosensing for Ultrasensitive Detection of microRNA, Analytical Chemistry, 2020, 92(1):853-858.

5. Xu Chun-Miao; Tang Man; Feng Jiao; Xia Hou-Fu; Wu Ling-Ling; Pang Dai-Wen; Chen Gang*; Zhang Zhi-Ling*, A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy, Lab on a Chip, 2020, 20(8):1418-1425.

6. Tang Man; Xia Hou-Fu; Xu Chun-Miao; Feng Jiao; Ren Jian-Gang; Miao Fan; Wu Min; Wu Ling-Ling; Pang Dai-Wen; Chen Gang*; Zhang Zhi-Ling*, Magnetic Chip Based Extracorporeal Circulation: A New Tool for Circulating Tumor Cell in Vivo Detection, Analytical Chemistry, 2019, 91(23):15260-15266.

7. Hong Shao-Li; Xiang Meng-Qi; Tang Man; Pang Dai-Wen; Zhang Zhi-Ling*, Ebola Virus Aptamers: From Highly Efficient Selection to Application on Magnetism-Controlled Chips, Analytical Chemistry, 2019, 91(5):3367-3373.

8. Wang Ji; Wang Cheng; Xu Na; Liu Zheng-Fei*; Pang Dai-Wen; Zhang Zhi-Ling*, A virus-induced kidney disease model based on organ-on-a-chip: Pathogenesis exploration of virus-related renal dysfunctions, Biomaterials, 2019, 219:119367.

9. Liu Cui; Xiao Guangjun*; Yang Mengli; Zou Bo*; Zhang Zhi-Ling*; Pang Dai-Wen, Mechanofluorochromic Carbon Nanodots: Controllable Pressure-Triggered Blue- and Red-Shifted Photoluminescence. Angewandte Chemie Interantional Edition, 2018, 57: 1893-1897.

10. Wu, Z.; Guo, W. J.; Bai, Y. Y.; Zhang, L.; Hu, J.; Pang, D. W.; Zhang, Z. L.*, Digital Single Virus Electrochemical Enzyme-Linked Immunoassay for Ultrasensitive H7N9 Avian Influenza Virus Counting. Anal. Chem. 2018, 90:1683-1690.