個(gè)人簡介
武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院教授，博士生導(dǎo)師；主要從事生物傳感分析、核酸納米技術(shù)、生物醫(yī)學(xué)材料等研究。致力于開發(fā)新型分析檢測方法與探針、開發(fā)先進(jìn)納米技術(shù)與材料、建立智能醫(yī)學(xué)診療材料與方法。截至目前，在相關(guān)領(lǐng)域國際權(quán)威學(xué)術(shù)期刊發(fā)表論文200余篇（包括100余篇通訊作者論文和20篇一作論文），一作及通訊作者論文包括1篇Chem. Rev.，1篇Chem. Soc. Rev.，1篇Acc. Chem. Res.，6篇J. Am. Chem. Soc.，12篇Angew. Chem.，1篇Nat. Commun.，1篇Nucleic Acids Res.，2篇Adv. Mater.，1篇Adv. Sci.，12篇Chem. Sci.，20篇Anal. Chem.，2篇Adv. Func. Mater.，3篇ACS Nano，2篇Nano lett.，12篇Small，3篇CCS Chem.，1篇Matter等，H因子62。獲批中、美專利5項(xiàng)，參編關(guān)于核酸納米技術(shù)書目章節(jié)4個(gè)。獲選武漢大學(xué)藍(lán)月亮獎(jiǎng)教金，獲評(píng)湖北省化學(xué)化工青年獎(jiǎng)。
教育經(jīng)歷
1999.09-2003.06 鄭州大學(xué)化學(xué)系 大學(xué)本科
2003.09-2009.01 中國科學(xué)院長春應(yīng)化所 博士研究生
工作經(jīng)歷
2009.02-014.06 希伯來大學(xué)化學(xué)系 博士后
2008.07-至今 武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院 教授
研究方向
生物分析與傳感、核酸化學(xué)生物學(xué)、核酸納米技術(shù)
代表成果
1. Shizhen He, Jinhua Shang, Yuqiu He, Fuan Wang*, Enzyme-free Dynamic DNA Reaction Networks for On-Demand Bioanalysis and Bioimaging. Acc. Chem. Res., 2024, 57, 533.
2. Jing Wang, Jinhua Shang, Shanshan Yu, Mengru Lin, Xue Gong, Xiaoqing Liu, Zhihong Liu*, Fuan Wang*, Bioorthogonal Activation of DNAzyme Nanoassembly for Synergistically Combined Genetherapy. Angew. Chem. Int. Ed., 2025, 64, e202417363.
3. Yuqiu He, Qing Wang, Chen Hong, Ruomeng Li, Jinhua Shang, Shanshan Yu, Xiaoqing Liu, Fuan Wang*, A Smart Deoxyribozyme-Programmable Catalytic DNA Logic Circuit for High-Contrast MicroRNA Imaging. Angew. Chem. Int. Ed., 2023, 62, e202307418.
4. Ruomeng Li, Yuxuan Zhu, Xue Gong, Yanping Zhang, Chen Hong, Yeqing Wan, Xiaoqing Liu, Fuan Wang*, Self-Stacking Autocatalytic Molecular Circuit with Minimal Catalytic DNA Assembly. J. Am. Chem. Soc., 2023, 145, 2999.
5. Shizhen He, Shanshan Yu, Ruomeng Li, Yingying Chen, Qing Wang, Yuqiu He, Xiaoqing Liu, Fuan Wang*, On-Site Nonenzymatic Orthogonal Activation of a Catalytic DNA Circuit for Self-Reinforced In Vivo MicroRNA Imaging. Angew. Chem. Int. Ed., 2022, 61, e202206529. (VIP PAPER)
6. Huimin Wang, Yuqiu He, Jie Wei, Hong Wang, Kang Ma, Yangjie Zhou, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, Construction of an Autocatalytic Hybridization Assembly Circuit for Amplified In Vivo MicroRNA Imaging. Angew. Chem. Int. Ed., 2022, 61, e202115489. (HOT PAPER)
7. Qing Wang, Kaiyue Tan, Hong Wang, Jinhua Shang, Yeqing Wan, Xiaoqing Liu, Xiaocheng Weng, Fuan Wang*, Orthogonal Demethylase-Activated Deoxyribozyme for Intracellular Imaging and Gene Regulation. J. Am. Chem. Soc., 2021, 143, 6895.
8. Jing Wang, Shanshan Yu, Qiong Wu, Xue Gong, Shizhen He, Jinhua Shang, Xiaoqing Liu, Fuan Wang*, A Self-Catabolic Multifunctional DNAzyme Nanosponge for Programmable Drug Delivery and Efficient Gene Silencing. Angew. Chem. Int. Ed., 2021, 60, 10766.
9. Jie Wei, Huimin Wang, Qiong Wu, Xue Gong, Kang Ma, Xiaoqing Liu and Fuan Wang*, A Smart Autocatalytic DNAzyme Biocircuit for in vivo MRI-Guided MicroRNA Imaging. Angew. Chem. Int. Ed., 2020, 59, 5965.
10. Xue Gong, Ruomeng Li, Jing Wang, Jie Wei, Kang Ma, Xiaoqing Liu, Fuan Wang*, A Smart Theranostic Nanocapsule for Spatiotemporally Programmable Photo-Genetherapy. Angew. Chem. Int. Ed., 2020, 59, 21648.
