個(gè)人簡(jiǎn)介
武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院副教授，博士生導(dǎo)師。多年來(lái)專(zhuān)注于小分子及納米熒光探針的設(shè)計(jì)合成、細(xì)胞及動(dòng)植物組織熒光成像、高效液相色譜/毛細(xì)管電泳等方面的科研工作。截止目前，申請(qǐng)者已主持國(guó)家自然科學(xué)基金面上項(xiàng)目1項(xiàng)，青年項(xiàng)目1項(xiàng)，湖北省自然科學(xué)基金面上項(xiàng)目1項(xiàng)，江蘇省自然科學(xué)基金青年項(xiàng)目1項(xiàng)，橫向課題多項(xiàng)，參與國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目1項(xiàng)，面上項(xiàng)目多項(xiàng)，在國(guó)內(nèi)外發(fā)表學(xué)術(shù)論文60余篇。
教育經(jīng)歷
2000.09-2004.06 武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院 大學(xué)本科
2004.09-2009.06 武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院 博士研究生
工作經(jīng)歷
2009.07-2016.09 武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院 講師
2014.09-2015.08 美國(guó)圣母大學(xué)化學(xué)與生物化學(xué)學(xué)院 訪問(wèn)學(xué)者
2016.10-至今 武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院 副教授
研究方向
熒光探針設(shè)計(jì)合成、生物成像、高效液相色譜/毛細(xì)管電泳
代表成果
1. S. He, W. Fang, X. Guo, H. Wang, A water-soluble two-photon fluorescent probe for rapid and reversible monitoring of redox state, Talanta, 2023, 253: 124066.
2. N. Wei, Y. Sun, X. Guo, H. Wang, Synthesis of sulfhydryl functionalized silicon quantum dots with high quantum yield for imaging of hypochlorite in cells and zebrafish, Microchimica Acta, 2022, 189: 329.
3. Y. Sun, L. Pang, X. Guo, H. Wang, Synthesis of metal ion tolerant Mn-doped fluorescence silicon quantum dots with green emission and its application for selective imaging of ·OH in living cells, Microchimica Acta, 2022, 189:
4. M. Fu, N. Wei, L. Pang, X. Guo, H. Wang, Red emission nitrogen and zinc co-doped carbon dots as fluorescent sensor for reversible detection of peroxynitrite in living cells, Sensors and Actuators B: Chemical, 2022, 351: 130939.
5. Y.J. Tang, S. He, X.F. Guo, H. Wang, A redox reversible endoplasmic reticulum-targeted fluorescent probe for revealing the redox status of living cells, Analyst, 2021, 146: 7740.
6. L. Pang, Y. Sun, X. Guo, H. Wang, Cell membrane-targeted near-infrared carbon dots for imaging of hydrogen sulfide released through the cell membrane, Sensors and Actuators B: Chemical, 2021, 345: 130403.
7. Y.J. Tang, W.L. Fang, K. Ren, X.F. Guo, H. Wang, A turn-on homodimer fluorescent probe based on homo-FRET for the sensing of biothiols in lysosome: a trial of a new turn-on strategy, Analyst, 2021, 146: 2974.
8. H. Wu, L. Pang, N. Wei, X. Guo, H. Wang, Nucleus-targeted N-doped carbon dots via DNA-binding for imaging of hypochlorous in cells and zebrafish, Sensors and Actuators B: Chemical, 2021, 333: 129626.
9. N. Wei, M. Wei, B. Huang, X. Guo, H. Wang, One-pot facile synthesis of green-emitting fluorescent silicon quantum dots for the highly selective and sensitive detection of nitrite in food samples, Dyes and Pigments, 2021, 184: 108848.
10. H. Yao, X. Guo, H. Wang, Simultaneous Quantitation of Intra- and Extracellular Nitric Oxide in Single Macrophage RAW 264.7 Cells by Capillary Electrophoresis with Laser-Induced Fluorescence Detection, Analytical Chemistry, 2020, 92: 11904.
